Randomized Clinical Trial Comparing Melatonin 3 mg, Amitriptyline 25 mg, and Placebo For Migraine Prevention

http://jnnp.bmj.com/content/87/10/1127.long

I question this because I take 5 mgs of Melatonin as needed. It has not improved my migraines at all. I’ve taken 100 mgs of Amitriptyline; it didn’t do anything. I worry that, if chosen for a migraine study, I will be placed on the placebo, but that’s a chance I am willing to take since I did throw my name into the ring for one that is local. The worst thing that can happen is, my migraines will continue being migraines. 😦

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